Product Description:
Wormental Fenbendazole Ivermectin 444 mg tablet within USA is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals.
Wormental Fenbendazole Ivermectin 444 mg tablet within USA is metabolized in the liver to oxfendazole, which is anthelmintic too; oxfendazole partially gets reduced back to fenbendazole in the liver and rumen. Also, fenbendazole itself is an active metabolite of another anthelmintic drug.
USE :
Wormental Fenbendazole Ivermectin 444 mg tablet within USA, [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, is widely used to treat pinworms, other helminthes, and a variety of parasitic infections in laboratory animals, livestock, companion animals, and people (1–3).
Abstract:
Wormental Fenbendazole Ivermectin 444 mg tablet within USA (Hoe 881) 5-(phenylthio)-2-benzimidazolecarbaminicacidmethylester in doses of 1-0 g and 1-5 g per person were effective against Ascaris and gave substantial egg count reductions against hookworm (mainly Necator americanus). The 1-5 g dose gave good results against Trichuris. In a trial with a suspension of Hoe 881 with a high specific surface of 25 m2/g there was no advantage over tablets with a specific surface of approximately 8 m2/g. Two doses of 500 mg given with an interval of 24 hours were no more effective than one dose of 1-0 g. In a comparative trial using Hoe 881 1-5 g, Pyrantel 10 mg/kg and placebo respectively Hoe 881 showed equal potency against hookworms and Acsaris as Pyrantel and good effectiveness against Trichuris. Pyrantel showed only moderate activity against Trichuris in this trial.
Fenbendazole in Covid:
A Wormental Fenbendazole Ivermectin 444 mg tablet within USA treatment reduced virus production by affecting the immediate early (IE) gene transcription and the synthesis of viron-associated proteins differentially. This is the first report showing that fenbendazole has antiviral effects.
Fenbendazole side effects in humans:
Giardia spp. are also considered susceptible to fenbendazole. Fenbendazole binds beta-tubulin subunits of microtubules, interfering with their polymerization. Side effects include vomiting and diarrhea, although both are considered rare.
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